所在学科专业：

人体解剖学

研究方向：

肿瘤治疗

讲授课程：

本科生：人体解剖学

教育经历：

1988.8–1991.8 第二军医大学，神经外科， 博士

1983.8–1986.8， 白求恩医科大学，人体解剖学系， 硕士

1977.2–1980.2， 白求恩医科大学，医疗系， 学士

工作经历：

2012.3-至今 吉林大学，白求恩医学院人体解剖学系,特聘教授1991.9 -1993.7 白求恩医科大学放射生物，副教授

1986.8-1988.8， 白求恩医科大学人体解剖系，讲师

1980.2-1983.8， 白求恩医科大学，人体解剖系，助教

科研项目：

1.国家自然科学基金项目：应用miR-17-92 cluster诱导的多潜能造血干细胞免疫治疗肿瘤的研究

学术论文：

1. miR-130b target NKD2 and regulates the WNT signaling to promote proliferation and inhibit apoptosis in osteocarcoma cells

2. Suppression of Her2/Neu mammary tumor development in mda7/IL-24 transgenic mice

3. Establishment and analysis of osteosarcoma cell sublines with different metastatic characteristics

4. The ets transcription factor Fli-1 in development, cancer and disease

5. mda-7/IL-24 Expression inhibits breast cancer through upregulation of growth arrest-specific gene 3 (gas3) and disruption of β1 integrin function

6. Drug-mediate inhibition of Fli-1 for treatment of leukemia

7.IL-24 Induces Expression of β4 Integrin, but Suppresses Anchorage-independent

8. Retroviral insertional activation of the Fli-3 locus in erythroleukemias encoding a cluster of microRNAs that convert Epo-induced differentiation to proliferation

9. Cyclin D1 is necessary but not sufficient for anchorage-independent growth of rat mammary tumor cells and is associated with resistance of the Copenhagen rat to mammary carcinogenesis

10. P45(NFE2) is a negative regulator of erythroid proliferation which contributes to the progression of Friend virus-induces erythroleukemias

获奖情况：

2015年中华医学科技奖贰等奖